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AccutaneKidneys

Under Federal Law, the manufacturer of a drug is required to revise its label to include a warning as soon as there is reasonable evidence of an association of a serious hazard with a drug.

The FDA has required Hoffmann-La Roche to change their label for Accutane many times. The most recent label under "adverse side effects" states - Urinary System: glomerulonephritis, nonspecific urogenital findings

Pursuant to FDA Rules and Regulation, the reporting of Adverse Side Effects is on a voluntary basis. In other words, the doctor, hospital, or other medical person or facility are not required by law to report an adverse side effect from a drug. The FDA reported that perhaps only one in one hundred side effects ever get reported. One could only imagine about how many serious Adverse Side Effects there are from taking Accutane, that have never been reported to anyone!

Glomerulonephritis

Acute glomerulonephritis is an inflammatory disease of both kidneys. Chronic glomerulonephritis can develop over a period of 10-20 years and is most often associated with other systemic diseases, including diabetes, malaria, hepatitis, or systemic lupus erythematosus.

Acute glomerulonephritis is an inflammation of the glomeruli, bundles of tiny vessels inside the kidneys. The damaged glomeruli cannot effectively filter waste products and excess water from the bloodstream to make urine. The kidneys appear enlarged, fatty, and congested.

It is thought that the kidney is damaged with exposure to the toxins that are excreted into the urine.

Mild glomerulonephritis may produce no symptoms, and diagnosis is made with laboratory studies of the urine and blood. Individuals with more severe cases of the disease may exhibit:

  • Fatigue
  • Nausea and vomiting
  • Shortness of breath
  • Disturbed vision
  • High blood pressure
  • Swelling, especially noted in the face, hands, feet, and ankles
  • Blood and protein in the urine, resulting in a smoky or slightly red appearance

The individual with chronic glomerulonephritis may discovery their condition with a routine physical exam revealing high blood pressure, or an eye exam showing vascular or hemorrhagic changes. The kidneys may be reduced to as little as one-fifth their normal size, consisting largely of fibrous tissues.

For more information, please visit the Family Practice Notebook.

FDA - Accutane Information Page


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If you believe you have been injured or have suffered a severe side effect from the use of Accutane, it may be that you are entitled to compensation.

It is important that if you contact our firm for a free case evaluation. Our lawyers will analyze your case and advise whether you are entitled to compensation. Contact us here















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